Cancer du poumon à petites cellules : prise en charge et nouveautés [Small-cell lung cancer: management and novelties]

Détails

ID Serval
serval:BIB_3F2FC3093CB5
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Cancer du poumon à petites cellules : prise en charge et nouveautés [Small-cell lung cancer: management and novelties]
Périodique
Revue medicale suisse
Auteur(s)
Abdelhamid K., Kakourou A., Degrauwe N., Nikolopoulou A., Bouchaab H., Peters S., Nguyen-Ngoc T., Mederos N.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
27/05/2020
Peer-reviewed
Oui
Volume
16
Numéro
695
Pages
1079-1085
Langue
français
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Small cell lung cancer is a recalcitrant malignancy with 5-year survival rates of less than 20%. In the majority of cases, patients have metastatic disease at diagnosis despite the new screening method by low-dose CT-scan. The high throughput sequencing has deepened our understanding of its biology. While the treatment of localized disease has changed little, the arrival of immune checkpoint inhibitors have revolutionized the management of extensive disease. At the same time, new strategies involving certain potential genetic targets are being analyzed on a large scale that could become valuable therapeutic alternatives in the future. Radiation therapy remains a very useful therapeutic modality in all stages of the disease. This article aims to review the epidemiology, molecular pathology, management and innovative therapies in small-cell lung cancer.
Mots-clé
Humans, Lung Neoplasms/drug therapy, Lung Neoplasms/radiotherapy, Lung Neoplasms/therapy, Small Cell Lung Carcinoma/drug therapy, Small Cell Lung Carcinoma/radiotherapy, Small Cell Lung Carcinoma/therapy, Survival Rate
Pubmed
Création de la notice
10/06/2020 22:10
Dernière modification de la notice
21/11/2020 7:26
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