Neurological adverse events associated with cancer immunotherapies: literature review and database development

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ID Serval
serval:BIB_3DC9613DC448
Type
Mémoire
Sous-type
(Mémoire de) maîtrise (master)
Collection
Publications
Institution
Titre
Neurological adverse events associated with cancer immunotherapies: literature review and database development
Auteur⸱e⸱s
DESBAILLETS N.
Directeur⸱rice⸱s
HOTTINGER A.
Détails de l'institution
Université de Lausanne, Faculté de biologie et médecine
Statut éditorial
Acceptée
Date de publication
2020
Langue
anglais
Nombre de pages
36
Résumé
In oncology, immunotherapeutic approaches have revolutionized the management of many cancer types. These treatments, although very effective, are associated with immune adverse events that are new and poorly known, including neurological adverse events. These side effects, if not recognized and treated early, present not only a risk to neurological function, but also to the oncological prognosis. This master's thesis briefly explains the different immunotherapeutic approaches used in oncology before presenting a systematic review of the literature identifying the neurological adverse events known to date in both the central and peripheral nervous systems. Management recommendations for each adverse event are also discussed. Finally, the architecture and functioning of a database allowing prospective capturing of patients with neurological complications related to immune oncology treatments are discussed.
Mots-clé
Immunotherapies, Cancer, Adverse Event, Neurologic
Création de la notice
09/09/2021 8:56
Dernière modification de la notice
04/10/2022 5:38
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