Pregnancy and reproduction in autoimmune rheumatic diseases.

Détails

Ressource 1Télécharger: serval:BIB_3CAB57DB1747.P001 (330.72 [Ko])
Etat: Public
Version: de l'auteur
Licence: Non spécifiée
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
ID Serval
serval:BIB_3CAB57DB1747
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Pregnancy and reproduction in autoimmune rheumatic diseases.
Périodique
Rheumatology
Auteur(s)
Ostensen M., Brucato A., Carp H., Chambers C., Dolhain R.J., Doria A., Förger F., Gordon C., Hahn S., Khamashta M., Lockshin M.D., Matucci-Cerinic M., Meroni P., Nelson J.L., Parke A., Petri M., Raio L., Ruiz-Irastorza G., Silva C.A., Tincani A., Villiger P.M., Wunder D., Cutolo M.
ISSN
1462-0332 (Electronic)
ISSN-L
1462-0324
Statut éditorial
Publié
Date de publication
2011
Volume
50
Numéro
4
Pages
657-664
Langue
anglais
Notes
licence nationale
Résumé
Despite evidence for the important role of oestrogens in the aetiology and pathophysiology of chronic immune/inflammatory diseases, the previous view of an unequivocal beneficial effect of oestrogens on RA compared with a detrimental effect on SLE has to be reconsidered. Likewise, the long-held belief that RA remits in the majority of pregnant patients has been challenged, and shows that only half of the patients experience significant improvement when objective disease activity measurements are applied. Pregnancies in patients with SLE are mostly successful when well planned and monitored interdisciplinarily, whereas a small proportion of women with APS still have adverse pregnancy outcomes in spite of the standard treatment. New prospective studies indicate better outcomes for pregnancies in women with rare diseases such as SSc and vasculitis. Fertility problems are not uncommon in patients with rheumatic disease and need to be considered in both genders. Necessary therapy, shortly before or during the pregnancy, demands taking into account the health of both mother and fetus. Long-term effects of drugs on offspring exposed in utero or during lactation is a new area under study as well as late effects of maternal rheumatic disease on children.
Pubmed
Web of science
Open Access
Oui
Création de la notice
13/04/2011 11:27
Dernière modification de la notice
25/09/2019 7:08
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