Pregnancy and reproduction in autoimmune rheumatic diseases.

Details

Ressource 1Download: serval:BIB_3CAB57DB1747.P001 (330.72 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_3CAB57DB1747
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Pregnancy and reproduction in autoimmune rheumatic diseases.
Journal
Rheumatology
Author(s)
Ostensen M., Brucato A., Carp H., Chambers C., Dolhain R.J., Doria A., Förger F., Gordon C., Hahn S., Khamashta M., Lockshin M.D., Matucci-Cerinic M., Meroni P., Nelson J.L., Parke A., Petri M., Raio L., Ruiz-Irastorza G., Silva C.A., Tincani A., Villiger P.M., Wunder D., Cutolo M.
ISSN
1462-0332 (Electronic)
ISSN-L
1462-0324
Publication state
Published
Issued date
2011
Volume
50
Number
4
Pages
657-664
Language
english
Notes
licence nationale
Abstract
Despite evidence for the important role of oestrogens in the aetiology and pathophysiology of chronic immune/inflammatory diseases, the previous view of an unequivocal beneficial effect of oestrogens on RA compared with a detrimental effect on SLE has to be reconsidered. Likewise, the long-held belief that RA remits in the majority of pregnant patients has been challenged, and shows that only half of the patients experience significant improvement when objective disease activity measurements are applied. Pregnancies in patients with SLE are mostly successful when well planned and monitored interdisciplinarily, whereas a small proportion of women with APS still have adverse pregnancy outcomes in spite of the standard treatment. New prospective studies indicate better outcomes for pregnancies in women with rare diseases such as SSc and vasculitis. Fertility problems are not uncommon in patients with rheumatic disease and need to be considered in both genders. Necessary therapy, shortly before or during the pregnancy, demands taking into account the health of both mother and fetus. Long-term effects of drugs on offspring exposed in utero or during lactation is a new area under study as well as late effects of maternal rheumatic disease on children.
Pubmed
Web of science
Open Access
Yes
Create date
13/04/2011 11:27
Last modification date
25/09/2019 7:08
Usage data