Long-term circulatory and renal consequences of intrauterine growth restriction.

Détails

ID Serval
serval:BIB_3B461EF7AC25
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Long-term circulatory and renal consequences of intrauterine growth restriction.
Périodique
Acta Paediatrica
Auteur⸱e⸱s
Simeoni U., Zetterström R.
ISSN
0803-5253 (Print)
ISSN-L
0803-5253
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
94
Numéro
7
Pages
819-824
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Résumé
Intrauterine growth restriction (IUGR) and probably also early postnatal altered nutrition in very-low-birthweight babies may, in the long term, be followed by the various disorders that are included in the metabolic syndrome. This discovery has raised a new paradigm about the background to cardiovascular disease, arterial hypertension, obesity, type 2 diabetes and dyslipidaemic disorders that play a prominent role in shortening human life. In this review article, present knowledge about the background to renal dysfunction as seen in IUGR is summarized. The way in which arterial hypertension and cardiovascular dysfunction may be programmed in IUGR is also speculated.
CONCLUSION: During the last decade, knowledge of the long-term consequences of IUGR has increased at a very rapid rate. At present, it is most important not only to develop efficient methods of preventing and diagnosing IUGR, but to work out follow-up and treatment programmes for the control of the disorders which may follow this condition. Proper postnatal feeding and infant growth may be essential for long-term outcome.
Mots-clé
Animals, Cardiovascular Diseases/etiology, Fetal Growth Retardation/physiopathology, Glomerular Filtration Rate, Glucocorticoids/physiology, Humans, Hypertension/etiology, Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Kidney/embryology, Kidney Diseases/etiology, Nephrons/embryology, Renin-Angiotensin System/physiology, Stress, Physiological/physiopathology, Time Factors
Pubmed
Web of science
Création de la notice
22/02/2015 12:25
Dernière modification de la notice
20/08/2019 14:31
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