Robust regression in biological assay: application to the evaluation of alternative experimental techniques.
Détails
ID Serval
serval:BIB_3A130C1B0DF4
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Robust regression in biological assay: application to the evaluation of alternative experimental techniques.
Périodique
Experientia
ISSN
0014-4754 (Print)
ISSN-L
0014-4754
Statut éditorial
Publié
Date de publication
1988
Volume
44
Numéro
10
Pages
857-873
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Robust Huber type regression and testing of linear hypotheses are adapted to statistical analysis of parallel line and slope ratio assays. They are applied in the evaluation of results of several experiments carried out in order to compare and validate alternatives to animal experimentation based on embryo and cell cultures. Computational procedures necessary for the application of robust methods of analysis used the conversational statistical package ROBSYS. Special commands for the analysis of parallel line and slope ratio assays have been added to ROBSYS.
Mots-clé
Animal Testing Alternatives, Animals, Biological Assay, Brain, Caffeine/toxicity, Cells, Cultured, Chick Embryo, Culture Techniques, Embryo, Mammalian, Phenytoin/toxicity, Rats, Regression Analysis, Software, Statistics as Topic
Pubmed
Web of science
Création de la notice
11/09/2011 14:23
Dernière modification de la notice
20/08/2019 14:29
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