Outlook: Roles of FSH and LH during the follicular phase: insight into natural cycle IVF
Détails
ID Serval
serval:BIB_38C3DA5DE0D1
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Outlook: Roles of FSH and LH during the follicular phase: insight into natural cycle IVF
Périodique
Reproductive Biomedicine Online
ISSN
1472-6483
Statut éditorial
Publié
Date de publication
11/2007
Peer-reviewed
Oui
Volume
15
Numéro
5
Pages
507-13
Notes
Journal Article
Review --- Old month value: Nov
Review --- Old month value: Nov
Résumé
A mounting interest in natural cycle IVF has challenged the medical community to better understand the mechanisms controlling the follicular phase and ovulation in particular, in an effort to optimize this procedure and its outcome. For practical reasons, the advancement of the follicular phase in the menstrual cycle is commonly timed according to the onset of last menses. However, this precludes knowing when the follicular phase truly begins and hampers the possibility of optimizing timing of late follicular-phase events, notably, the triggering of ovulation. Clinicians, therefore, use surrogate markers of follicular maturation, such as oestrogen production and follicular size. Because it is impossible to identify the low-amplitude intercycle basal FSH signal, efforts have reverted toward controlling when it takes place, either with exogenous oestrogen or with oral contraceptives. In the late follicular phase, the occurrence of LH surge results from a balance between the opposite effects of rising oestrogen concentrations, which favour the LH surge, and the opposing effects mediated by the gonadotrophin surge-attenuating factor, a peptide of ovarian origin. This review looks into the mechanisms that control these two hinges of the follicular phase, the basal FSH signal and LH surge, in the context of optimizing natural cycle IVF.
Mots-clé
Contraceptives, Oral/therapeutic use
Estrogens/physiology/therapeutic use
Female
Fertilization in Vitro/*methods
Follicle Stimulating Hormone/*physiology
Follicular Phase/*physiology
Gonadal Hormones/physiology
Humans
Infertility, Female/drug therapy
Luteinizing Hormone/*physiology
Ovarian Follicle/*physiology
Proteins/physiology
Pubmed
Web of science
Open Access
Oui
Création de la notice
28/02/2008 12:37
Dernière modification de la notice
07/10/2019 9:12