Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis.

Rozot, V.; Patrizia, A.; Vigano, S.; Mazza-Stalder, J.; Idrizi, E.; Day, C.L.; Perreau, M.; Lazor-Blanchet, C.; Ohmiti, K.; Goletti, D.; Bart, P.A.; Hanekom, W.; Scriba, T.J.; Nicod, L.; Pantaleo, G.; Harari, A.

doi:10.1093/cid/ciu795

Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis.

Détails

Télécharger: BIB_35203E0F848B.P001.pdf (343.86 [Ko])
Etat: Public
Version: de l'auteur⸱e

ID Serval

serval:BIB_35203E0F848B

Type

Article: article d'un périodique ou d'un magazine.

Collection

Publications

Institution

UNIL/CHUV

Titre

Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis.

Périodique

Clinical Infectious Diseases

Auteur⸱e⸱s

Rozot V., Patrizia A., Vigano S., Mazza-Stalder J., Idrizi E., Day C.L., Perreau M., Lazor-Blanchet C., Ohmiti K., Goletti D., Bart P.A., Hanekom W., Scriba T.J., Nicod L., Pantaleo G., Harari A.

ISSN

1537-6591 (Electronic)

ISSN-L

1058-4838

Statut éditorial

Publié

Date de publication

2015

Peer-reviewed

Oui

Volume

Numéro

Pages

432-437

Langue

anglais

Notes

Publication types: Journal Article Publication Status: ppublish
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work properly cited. For commercial re-use, please contact journals.permissions@oup.com.

Résumé

Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.

URN

urn:nbn:ch:serval-BIB_35203E0F848B4

OAI-PMH

oai:serval.unil.ch:BIB_35203E0F848B

DOI

10.1093/cid/ciu795

Pubmed

25362202

Web of science

000349761600023

Open Access

Oui