Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis.

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Serval ID
serval:BIB_35203E0F848B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis.
Journal
Clinical Infectious Diseases
Author(s)
Rozot V., Patrizia A., Vigano S., Mazza-Stalder J., Idrizi E., Day C.L., Perreau M., Lazor-Blanchet C., Ohmiti K., Goletti D., Bart P.A., Hanekom W., Scriba T.J., Nicod L., Pantaleo G., Harari A.
ISSN
1537-6591 (Electronic)
ISSN-L
1058-4838
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
60
Number
3
Pages
432-437
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work properly cited. For commercial re-use, please contact journals.permissions@oup.com.
Abstract
Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.
Pubmed
Web of science
Open Access
Yes
Create date
08/12/2014 9:12
Last modification date
20/08/2019 14:22
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