Prognosis of Patients with Chronic and Hospital-Acquired Anaemia After Acute Coronary Syndromes.

Détails

ID Serval
serval:BIB_340120A399E3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Prognosis of Patients with Chronic and Hospital-Acquired Anaemia After Acute Coronary Syndromes.
Périodique
Journal of cardiovascular translational research
Auteur(s)
Mahendiran T., Nanchen D., Gencer B., Meier D., Klingenberg R., Räber L., Carballo D., Matter C.M., Lüscher T.F., Windecker S., Mach F., Rodondi N., Muller O., Fournier S.
ISSN
1937-5395 (Electronic)
ISSN-L
1937-5387
Statut éditorial
Publié
Date de publication
08/2020
Peer-reviewed
Oui
Volume
13
Numéro
4
Pages
618-628
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Discharge anaemia is common following acute coronary syndromes (ACS). However, it is unknown if chronic anaemia (CA) and hospital-acquired anaemia (HAA) are associated with similar outcomes. In this retrospective analysis of 4083 ACS admissions treated with percutaneous coronary intervention in Switzerland (SPUM-ACS registry), 1896 patients (46.4%) had discharge anaemia (CA: n = 643 (15.7%) vs. HAA: n = 1253 (30.7%)). Landmark analysis that matched patients with CA (n = 504) and HAA (n = 866) with non-anaemic patients found increased 1-year major adverse cardiovascular events (cardiovascular mortality, myocardial infarction, stroke) among patients with CA (6.9% vs. 3.0%, HR 2.073, 95% CI 1.039-4.134, p = 0.039) and HAA (3.8% vs. 2.3%, HR 1.772, 95% CI 1.002-3.232, p = 0.049). Only CA was associated with increased 1-year all-cause mortality (7.9% vs. 1.6%, HR 4.255, 95% CI 1.950-9.284, p < 0.001). CA and HAA were associated with poor 1-year cardiovascular outcomes. Only CA was associated with increased all-cause mortality suggesting that HAA and CA represent distinct subclinical entities.
Mots-clé
Acute coronary syndrome, Anaemia, Invasive coronary angiography
Pubmed
Web of science
Création de la notice
12/12/2019 15:43
Dernière modification de la notice
02/09/2020 6:22
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