Prognosis of Patients with Chronic and Hospital-Acquired Anaemia After Acute Coronary Syndromes.

Details

Serval ID
serval:BIB_340120A399E3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Prognosis of Patients with Chronic and Hospital-Acquired Anaemia After Acute Coronary Syndromes.
Journal
Journal of cardiovascular translational research
Author(s)
Mahendiran T., Nanchen D., Gencer B., Meier D., Klingenberg R., Räber L., Carballo D., Matter C.M., Lüscher T.F., Windecker S., Mach F., Rodondi N., Muller O., Fournier S.
ISSN
1937-5395 (Electronic)
ISSN-L
1937-5387
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Discharge anaemia is common following acute coronary syndromes (ACS). However, it is unknown if chronic anaemia (CA) and hospital-acquired anaemia (HAA) are associated with similar outcomes. In this retrospective analysis of 4083 ACS admissions treated with percutaneous coronary intervention in Switzerland (SPUM-ACS registry), 1896 patients (46.4%) had discharge anaemia (CA: n = 643 (15.7%) vs. HAA: n = 1253 (30.7%)). Landmark analysis that matched patients with CA (n = 504) and HAA (n = 866) with non-anaemic patients found increased 1-year major adverse cardiovascular events (cardiovascular mortality, myocardial infarction, stroke) among patients with CA (6.9% vs. 3.0%, HR 2.073, 95% CI 1.039-4.134, p = 0.039) and HAA (3.8% vs. 2.3%, HR 1.772, 95% CI 1.002-3.232, p = 0.049). Only CA was associated with increased 1-year all-cause mortality (7.9% vs. 1.6%, HR 4.255, 95% CI 1.950-9.284, p < 0.001). CA and HAA were associated with poor 1-year cardiovascular outcomes. Only CA was associated with increased all-cause mortality suggesting that HAA and CA represent distinct subclinical entities.
Keywords
Acute coronary syndrome, Anaemia, Invasive coronary angiography
Pubmed
Create date
12/12/2019 15:43
Last modification date
24/12/2019 7:26
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