Structural insights into PYR/PYL/RCAR ABA receptors and PP2Cs.

Détails

ID Serval
serval:BIB_311B8A0FB2D7
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Structural insights into PYR/PYL/RCAR ABA receptors and PP2Cs.
Périodique
Plant science
Auteur(s)
Santiago J., Dupeux F., Betz K., Antoni R., Gonzalez-Guzman M., Rodriguez L., Márquez J.A., Rodriguez P.L.
ISSN
1873-2259 (Electronic)
ISSN-L
0168-9452
Statut éditorial
Publié
Date de publication
01/2012
Peer-reviewed
Oui
Volume
182
Pages
3-11
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
Abscisic acid (ABA) plays an essential function in plant physiology since it is required for biotic and abiotic stress responses as well as control of plant growth and development. A new family of soluble ABA receptors, named PYR/PYL/RCAR, has emerged as ABA sensors able to inhibit the activity of specific protein phosphatases type-2C (PP2Cs) in an ABA-dependent manner. The structural and functional mechanism by which ABA is perceived by these receptors and consequently leads to inhibition of the PP2Cs has been recently elucidated. The module PYR/PYL/RCAR-ABA-PP2C offers an elegant and unprecedented mechanism to control phosphorylation signaling cascades in a ligand-dependent manner. The knowledge of their three-dimensional structures paves the way to the design of ABA agonists able to modulate the plant stress response.
Mots-clé
Abscisic Acid/chemistry, Abscisic Acid/metabolism, Arabidopsis/metabolism, Arabidopsis Proteins/chemistry, Arabidopsis Proteins/metabolism, Carrier Proteins/chemistry, Carrier Proteins/metabolism, Phosphoprotein Phosphatases/chemistry, Phosphoprotein Phosphatases/metabolism, Plant Growth Regulators/chemistry, Plant Growth Regulators/metabolism, Plant Proteins/chemistry, Plant Proteins/metabolism, Protein Phosphatase 2C, Stress, Physiological, Structure-Activity Relationship
Pubmed
Web of science
Création de la notice
10/01/2019 17:21
Dernière modification de la notice
21/08/2019 5:35
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