Transfer factor for carbon monoxide: a glance behind the scene.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_3094DAF6EAA4
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Transfer factor for carbon monoxide: a glance behind the scene.
Périodique
Swiss Medical Weekly
Auteur(s)
Fitting J.W.
ISSN
1424-7860
Statut éditorial
Publié
Date de publication
2004
Peer-reviewed
Oui
Volume
134
Numéro
29-30
Pages
413-418
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Résumé
The transfer factor for carbon monoxide (TLCO) is widely used in pulmonary function laboratories because it represents a unique non-invasive window on pulmonary microcirculation. The TLCO is the product of two primary measurements, the alveolar volume (VA) and the CO transfer coefficient (KCO). This test is most informative when VA and KCO are examined, together with their product TLCO. In a normal lung, a low VA due to incomplete expansion is associated with an elevated KCO, resulting in a mildly reduced TLCO. Thus, in case of low VA, a seemingly "normal KCO" must be interpreted as an abnormal gas transfer. The most common clinical conditions associated with an abnormal TLCO are characterised by a limited number of patterns for VA and KCO: incomplete lung expansion, discrete loss of alveolar units, diffuse loss of alveolar units, emphysema, pulmonary vascular disorders, high pulmonary blood volume, alveolar haemorrhage.
Mots-clé
Adult, Aged, Airway Resistance, Carbon Monoxide, Female, Humans, Lung Diseases, Male, Middle Aged, Pulmonary Alveoli, Pulmonary Circulation, Pulmonary Diffusing Capacity, Pulmonary Gas Exchange, Respiratory Function Tests, Respiratory Muscles, Total Lung Capacity
Pubmed
Web of science
Création de la notice
25/01/2008 9:43
Dernière modification de la notice
20/08/2019 13:15
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