Pictures of focal nodular hyperplasia and hepatocellular adenomas.
Détails
ID Serval
serval:BIB_303A656EFFD9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Pictures of focal nodular hyperplasia and hepatocellular adenomas.
Périodique
World Journal of Hepatology
ISSN
1948-5182 (Electronic)
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
6
Numéro
8
Pages
580-595
Langue
anglais
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Résumé
This practical atlas aims to help liver and non liver pathologists to recognize benign hepatocellular nodules on resected specimen. Macroscopic and microscopic views together with immunohistochemical stains illustrate typical and atypical aspects of focal nodular hyperplasia and of hepatocellular adenoma, including hepatocellular adenomas subtypes with references to clinical and imaging data. Each step is important to make a correct diagnosis. The specimen including the nodule and the non-tumoral liver should be sliced, photographed and all different looking areas adequately sampled for paraffin inclusion. Routine histology includes HE, trichrome and cytokeratin 7. Immunohistochemistry includes glutamine synthase and according to the above results additional markers such as liver fatty acid binding protein, C reactive protein and beta catenin may be realized to differentiate focal nodular hyperplasia from hepatocellular adenoma subtypes. Clues for differential diagnosis and pitfalls are explained and illustrated.
Pubmed
Open Access
Oui
Création de la notice
16/01/2015 12:07
Dernière modification de la notice
20/08/2019 13:14