On the Host Side of the Hepatitis E Virus Life Cycle.

Détails

Ressource 1Télécharger: 32456000_BIB_2FFD9F83A168.pdf (1535.00 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_2FFD9F83A168
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
On the Host Side of the Hepatitis E Virus Life Cycle.
Périodique
Cells
Auteur(s)
Oechslin N., Moradpour D., Gouttenoire J.
ISSN
2073-4409 (Electronic)
ISSN-L
2073-4409
Statut éditorial
Publié
Date de publication
22/05/2020
Peer-reviewed
Oui
Volume
9
Numéro
5
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
Hepatitis E virus (HEV) infection is one of the most common causes of acute hepatitis in the world. HEV is an enterically transmitted positive-strand RNA virus found as a non-enveloped particle in bile as well as stool and as a quasi-enveloped particle in blood. Current understanding of the molecular mechanisms and host factors involved in productive HEV infection is incomplete, but recently developed model systems have facilitated rapid progress in this area. Here, we provide an overview of the HEV life cycle with a focus on the host factors required for viral entry, RNA replication, assembly and release. Further developments of HEV model systems and novel technologies should yield a broader picture in the future.
Mots-clé
HEV, host factor, particle production, viral replication, virus entry
Pubmed
Open Access
Oui
Création de la notice
10/06/2020 21:41
Dernière modification de la notice
15/01/2021 7:08
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