Occurrence and new mutations involved in rifampicin-resistant Propionibacterium acnes strains isolated from biofilm or device-related infections.
Détails
ID Serval
serval:BIB_2F40B4E02F57
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Occurrence and new mutations involved in rifampicin-resistant Propionibacterium acnes strains isolated from biofilm or device-related infections.
Périodique
Anaerobe
ISSN
1095-8274 (Electronic)
ISSN-L
1075-9964
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
34
Pages
116-119
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
We described for the first time the amino acid substitutions conferring rifampicin resistance in eight Propionibacterium acnes strains isolated from patients with biofilm or device-related infections. We identified different mutations in cluster I and one mutation, never reported, in cluster II of the rpoB gene (I480V) associated with the most frequent one in cluster I (S442L). Half of the patients previously received treatment with rifampicin.
Mots-clé
Adult, Aged, Aged, 80 and over, Amino Acid Substitution, Anti-Bacterial Agents/pharmacology, Biofilms, Catheter-Related Infections/microbiology, DNA-Directed RNA Polymerases/genetics, Drug Resistance, Bacterial, Female, Gram-Positive Bacterial Infections/microbiology, Humans, Male, Middle Aged, Molecular Sequence Data, Mutation, Missense, Propionibacterium acnes/drug effects, Propionibacterium acnes/isolation & purification, Rifampin/pharmacology, Sequence Analysis, DNA
Pubmed
Web of science
Création de la notice
24/08/2015 16:28
Dernière modification de la notice
20/08/2019 13:13
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