Validation of the revised international prognostic scoring system (IPSS-R) in patients with myelodysplastic syndrome: a multicenter study.

Détails

ID Serval
serval:BIB_2CC848AADF0C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Validation of the revised international prognostic scoring system (IPSS-R) in patients with myelodysplastic syndrome: a multicenter study.
Périodique
Leukemia Research
Auteur(s)
Neukirchen J., Lauseker M., Blum S., Giagounidis A., Lübbert M., Martino S., Siragusa S., Schlenk R.F., Platzbecker U., Hofmann W.K., Götze K., Palumbo G.A., Magrin S., Kündgen A., Aul C., Hildebrandt B., Hasford J., Kobbe G., Haas R., Germing U.
ISSN
1873-5835 (Electronic)
ISSN-L
0145-2126
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
38
Numéro
1
Pages
57-64
Langue
anglais
Notes
Publication types: Journal Article ; Multicenter Study ; Validation StudiesPublication Status: ppublish
Résumé
The revised IPSS (IPSS-R) was developed aiming at a better prognostication, taking into account patients treated with best supportive care. We herein validated this model on the basis of data from 1314 patients who received BSC only as well as patients who underwent induction chemotherapy (n=214) or allogeneic transplantation (n=167). We could demonstrate a clear distinction of the IPSS-R risk categories with regard to survival and risk of AML evolution in all patient cohorts. When comparing IPSS-R, IPSS, WHO prognostic scoring system (WPSS) and Duesseldorf score, the best results regarding the ability to predict survival were obtained by the IPSS-R.
Mots-clé
Acute Disease, Adolescent, Adult, Aged, Aged, 80 and over, Disease Progression, Female, Humans, Leukemia, Myeloid/pathology, Leukemia, Myeloid/therapy, Male, Middle Aged, Multivariate Analysis, Myelodysplastic Syndromes/pathology, Myelodysplastic Syndromes/therapy, Prognosis, Reproducibility of Results, Risk Assessment/methods, Risk Factors, Survival Analysis, Young Adult
Pubmed
Web of science
Création de la notice
18/10/2016 14:13
Dernière modification de la notice
20/08/2019 13:11
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