La léiomyomatose péritonéale disséminée: profil immunohistochimique et origine [Leiomyomatosis peritonealis disseminata: immunohistochemical profile and origin]

Détails

ID Serval
serval:BIB_289B532679B5
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
La léiomyomatose péritonéale disséminée: profil immunohistochimique et origine [Leiomyomatosis peritonealis disseminata: immunohistochemical profile and origin]
Périodique
Annales de pathologie
Auteur⸱e⸱s
Bucher M., Pusztaszeri M., Bouzourene H.
ISSN
0242-6498
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
26
Numéro
3
Pages
207-210
Langue
français
Notes
Publication types: Case Reports ; English Abstract ; Journal Article - Publication Status: ppublish
Résumé
Leiomyomatosis peritonealis disseminata (LPD) is a rare disease presenting as multiple peritoneal nodules of smooth muscle cells, mimicking peritoneal carcinomatosis. This disease usually pursues a benign course. We report one case of LPD in a 32-year-old woman, G2P1, without gynecological history. At term, she had an elective caesarean section during which several firm peritoneal nodules, ranging from 0.2 to 0.4 mm, were found. Microscopic examination showed a smooth-muscle cell proliferation with no mitosis, no atypia and no necrosis. Immunohistochemical analysis showed diffuse and strong staining for progesterone receptors and partial expression of estrogen receptors. The cells coexpressed smooth muscle actin, desmin, h-caldesmon, calretinin, WT1, and CD117 (KIT). They were weakly positive for EMA but negative for CD34. Proliferation index was low with 5% of cells being positive for MIB-1. This case of LPD proved to have an unusual immunohistochemistry profile raising the question of its real origin.
Mots-clé
Adult, Antigens, CD, Cesarean Section, Female, Humans, Immunohistochemistry, Leiomyoma, Mitosis, Peritoneal Neoplasms, Pregnancy
Pubmed
Web of science
Création de la notice
29/01/2008 19:36
Dernière modification de la notice
20/08/2019 14:08
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