La léiomyomatose péritonéale disséminée: profil immunohistochimique et origine [Leiomyomatosis peritonealis disseminata: immunohistochemical profile and origin]

Details

Serval ID
serval:BIB_289B532679B5
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
La léiomyomatose péritonéale disséminée: profil immunohistochimique et origine [Leiomyomatosis peritonealis disseminata: immunohistochemical profile and origin]
Journal
Annales de pathologie
Author(s)
Bucher M., Pusztaszeri M., Bouzourene H.
ISSN
0242-6498
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
26
Number
3
Pages
207-210
Language
french
Notes
Publication types: Case Reports ; English Abstract ; Journal Article - Publication Status: ppublish
Abstract
Leiomyomatosis peritonealis disseminata (LPD) is a rare disease presenting as multiple peritoneal nodules of smooth muscle cells, mimicking peritoneal carcinomatosis. This disease usually pursues a benign course. We report one case of LPD in a 32-year-old woman, G2P1, without gynecological history. At term, she had an elective caesarean section during which several firm peritoneal nodules, ranging from 0.2 to 0.4 mm, were found. Microscopic examination showed a smooth-muscle cell proliferation with no mitosis, no atypia and no necrosis. Immunohistochemical analysis showed diffuse and strong staining for progesterone receptors and partial expression of estrogen receptors. The cells coexpressed smooth muscle actin, desmin, h-caldesmon, calretinin, WT1, and CD117 (KIT). They were weakly positive for EMA but negative for CD34. Proliferation index was low with 5% of cells being positive for MIB-1. This case of LPD proved to have an unusual immunohistochemistry profile raising the question of its real origin.
Keywords
Adult, Antigens, CD, Cesarean Section, Female, Humans, Immunohistochemistry, Leiomyoma, Mitosis, Peritoneal Neoplasms, Pregnancy
Pubmed
Web of science
Create date
29/01/2008 19:36
Last modification date
20/08/2019 14:08
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