Effect of increasing heart rate in patients with aortic regurgitation. Effect of incremental atrial pacing on scintigraphic, hemodynamic and thermodilution measurements
Détails
ID Serval
serval:BIB_2691D58D350D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Effect of increasing heart rate in patients with aortic regurgitation. Effect of incremental atrial pacing on scintigraphic, hemodynamic and thermodilution measurements
Périodique
American Journal of Cardiology
ISSN
0002-9149 (Print)
Statut éditorial
Publié
Date de publication
06/1982
Volume
49
Numéro
8
Pages
1860-7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jun
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Jun
Résumé
This study was performed to assess the effect of pacing-induced tachycardia in patients with aortic regurgitation. In 12 patients (5 men and 7 women with a mean age of 53 years) with aortic regurgitation, left ventricular end-diastolic and end-systolic volume indexes were measured with multigated equilibrium blood pool imaging, and forward cardiac index was determined with thermodilution, both at rest (mean heart rate +/- standard deviation 72 +/- 8 beats/min) and during atrial pacing at 100 and 120 beats/min. Pacing caused a decremental reduction in left ventricular end-diastolic and end-systolic volume indexes and radionuclide-determined stroke volume index but no change in radionuclide-determined cardiac index or left ventricular ejection fraction. Forward cardiac index increased incrementally from the baseline value at rest to that at 120 beats/min despite a decremental reduction in stroke volume index. There was a stepwise decrease in regurgitant volume/stroke (46 +/- 20 ml/m2 at baseline, 27 +/- 15 at 120 beats/min; p less than 0.05) but no change in regurgitant volume/min (3.38 +/- 1.80 liters/min per m2 at baseline, 3.22 +/- 1.78 at 120 beats/min; difference not significant [NS]) or regurgitant fraction (0.54 +/- 0.13 at baseline, 0.49 +/- 0.13 at 120 beats/min; NS). Mean femoral arterial, pulmonary arterial and pulmonary capillary wedge pressures did not change with pacing.
Mots-clé
Aortic Valve Insufficiency/diagnosis/*physiopathology
Blood Pressure
Cardiac Output
*Cardiac Pacing, Artificial
Erythrocytes
Female
Heart/radionuclide imaging
Heart Catheterization
Heart Rate
Humans
Male
Middle Aged
Sodium Pertechnetate Tc 99m
Stroke Volume
Technetium/diagnostic use
Thermodilution
Pubmed
Web of science
Création de la notice
25/01/2008 15:00
Dernière modification de la notice
20/08/2019 14:05