Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.

Détails

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ID Serval
serval:BIB_22367B6D2F75
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
UNIL/CHUV
Titre
Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.
Périodique
Radiotherapy and oncology
Auteur⸱e⸱s
Riesterer O., Ciernik I.F., Stahel R.A., Xyrafas A., Aebersold D.M., Plasswilm L., Mahmut Ozsahin E., Zwahlen D.R., Nackaerts K., Zimmermann F., Sabrina Stark L., Weder W., Krayenbuehl J.
Collaborateur⸱rice⸱s
Swiss Group for Clinical Cancer Research (SAKK)
ISSN
1879-0887 (Electronic)
ISSN-L
0167-8140
Statut éditorial
Publié
Date de publication
09/2019
Peer-reviewed
Oui
Volume
138
Pages
121-125
Langue
anglais
Notes
Publication types: Clinical Trial, Phase II ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Postoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial SAKK17/04. The relapse rate within the high and/or low-dose PTV without previous distant failure was 24%, the isolated in-field-relapse rate within the PTVs was 5% and the distant relapse rate outside of the PTVs was 81%. Clinical outcome was mainly determined by distant disease progression outside of the radiation field.
Mots-clé
Aged, Dose-Response Relationship, Radiation, Female, Follow-Up Studies, Humans, Lung Neoplasms/pathology, Lung Neoplasms/radiotherapy, Lung Neoplasms/surgery, Male, Mesothelioma/pathology, Mesothelioma/radiotherapy, Mesothelioma/surgery, Middle Aged, Neoplasm Recurrence, Local/diagnosis, Neoplasm Recurrence, Local/pathology, Pleural Neoplasms/pathology, Pleural Neoplasms/radiotherapy, Pleural Neoplasms/surgery, Pneumonectomy, Radiotherapy, Adjuvant, Treatment Outcome, Extrapleural pneumonectomy, Mesothelioma, Multimodal therapy, Radiation therapy, Radiotherapy, Trimodal therapy
OAI-PMH
oai:serval.unil.ch:BIB_22367B6D2F75
DOI
10.1016/j.radonc.2019.05.024
Pubmed
31252293
Web of science
000482210600018
Création de la notice
18/07/2019 17:58
Dernière modification de la notice
20/06/2020 6:18
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