Platelet glycoprotein IIb/IIIa blockade in acute ischemic stroke.

Détails

ID Serval
serval:BIB_21105
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Platelet glycoprotein IIb/IIIa blockade in acute ischemic stroke.
Périodique
Cerebrovascular Diseases (basel, Switzerland)
Auteur(s)
Bogousslavsky J., Leclerc J.R.
ISSN
1015-9770 (Print)
ISSN-L
1015-9770
Statut éditorial
Publié
Date de publication
2001
Volume
11
Numéro
4
Pages
287-293
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
While thrombolytic therapy is approved in the United States and Canada for treatment of acute ischemic stroke, only a small number of patients are currently treated. Additional agents that could restore or improve cerebral flow are needed. Based on the experience in acute coronary syndromes, reperfusion agents such as platelet glycoprotein IIb/IIIa antagonists, alone or in combination with reduced doses of thrombolytic agents, have the potential for improving the safety and efficacy of recombinant tissue plasminogen activator (rt-PA). In addition, these newer agents may permit extension beyond the current 3-hour window from symptom onset used for systemic rt-PA.
Mots-clé
Acute Disease, Brain Ischemia/drug therapy, Humans, Platelet Aggregation Inhibitors/therapeutic use, Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors, Stroke/blood, Stroke/drug therapy, Thrombosis/prevention & control
Pubmed
Web of science
Création de la notice
19/11/2007 12:16
Dernière modification de la notice
20/08/2019 12:57
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