Cytokines in the neuroendocrine system.

Détails

ID Serval
serval:BIB_1F3862435B93
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Cytokines in the neuroendocrine system.
Périodique
International Reviews of Immunology
Auteur(s)
Gaillard R.C.
ISSN
0883-0185
Statut éditorial
Publié
Date de publication
1998
Peer-reviewed
Oui
Volume
17
Numéro
1-4
Pages
181-216
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Cytokines are important partners in the bidirectional network interrelating the immune and the neuroendocrine systems. These substances and their specific receptors, initially thought to be exclusively present in the immune system, have recently been shown to be also expressed in the neuroendocrine system. Cytokines can modulate the responses of all endocrine axes by acting at both the central and the peripheral levels. To explain how systemic cytokines may gain access to the brain, several mechanisms have been proposed, including an active transport through the blood-brain barrier, a passage at the circumventricular organ level, as well as a neuronal pathway through the vagal nerve. The immune-neuroendocrine interactions are involved in numerous physiological and pathophysiological conditions and seem to play an important role to maintain homeostasis.
Mots-clé
Animals, Cytokines/biosynthesis, Cytokines/metabolism, Humans, Neurosecretory Systems/immunology, Neurosecretory Systems/metabolism, Receptors, Cytokine/biosynthesis, Receptors, Cytokine/physiology
Pubmed
Création de la notice
15/02/2008 16:57
Dernière modification de la notice
20/08/2019 12:55
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