Small intestinal microbiota: from taxonomic composition to metabolism.
Détails
Télécharger: 38503579.pdf (2150.56 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_1EAF55E4ABF5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Small intestinal microbiota: from taxonomic composition to metabolism.
Périodique
Trends in microbiology
ISSN
1878-4380 (Electronic)
ISSN-L
0966-842X
Statut éditorial
Publié
Date de publication
10/2024
Peer-reviewed
Oui
Volume
32
Numéro
10
Pages
970-983
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
The small intestinal microbiota (SIM) is essential for gastrointestinal health, influencing digestion, immune modulation, and nutrient metabolism. Unlike the colonic microbiota, the SIM has been poorly characterized due to sampling challenges and ethical considerations. Current evidence suggests that the SIM consists of five core genera and additional segment-specific taxa. These bacteria closely interact with the human host, regulating nutrient absorption and metabolism. Recent work suggests the presence of two forms of small intestinal bacterial overgrowth, one dominated by oral bacteria (SIOBO) and a second dominated by coliform bacteria. Less invasive sampling techniques, omics approaches, and mechanistic studies will allow a more comprehensive understanding of the SIM, paving the way for interventions engineering the SIM towards better health.
Mots-clé
Humans, Gastrointestinal Microbiome, Bacteria/classification, Bacteria/genetics, Bacteria/metabolism, Intestine, Small/microbiology, Animals, duodenum, ileum, jejunum, nutrient absorption, small intestinal bacterial overgrowth, small intestinal microbiota
Pubmed
Open Access
Oui
Création de la notice
25/03/2024 12:04
Dernière modification de la notice
11/10/2024 19:17