Surgery and granulocyte transfusions for life-threatening infections in chronic granulomatous disease.

Détails

ID Serval
serval:BIB_1AD1BE77CFD2
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Surgery and granulocyte transfusions for life-threatening infections in chronic granulomatous disease.
Périodique
Helvetica paediatrica acta
Auteur⸱e⸱s
Fanconi S., Seger R., Gmür J., Willi U., Schaer G., Spiess H., Otto R., Hitzig W.H.
ISSN
0018-022X
Statut éditorial
Publié
Date de publication
1985
Volume
40
Numéro
4
Pages
277-84
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Résumé
We report two patients with chronic granulomatous disease (CGD) and life-threatening infections: a 10 10/12-year-old boy had Aspergillus fumigatus spondylitis with destruction of the 11th vertebral body and paravertebral abscess formation, and an 8 5/12-year-old boy had multiple Staphylococcus aureus hepatic abscesses with subphrenic abscess formation. Both patients failed to respond to intense antimicrobial therapy but showed a remarkable recovery following surgical drainage combined with granulocyte transfusions. These results suggest that antimicrobial therapy and surgical drainage followed by granulocyte transfusions may be the ideal mode of treatment for severe infections in patients with CGD.
Mots-clé
Amphotericin B, Blood Transfusion, Child, Drug Combinations, Flucytosine, Granulocytes, Granulomatous Disease, Chronic, Humans, Liver Abscess, Male, Spondylitis, Staphylococcal Infections, Subphrenic Abscess, Sulfamethoxazole, Trimethoprim, Trimethoprim-Sulfamethoxazole Combination
Pubmed
Web of science
Création de la notice
25/01/2008 10:06
Dernière modification de la notice
20/08/2019 12:51
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