Knowing where and getting there: a human navigation network.

Détails

ID Serval
serval:BIB_18E687BDD4F4
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Knowing where and getting there: a human navigation network.
Périodique
Science
Auteur(s)
Maguire E.A., Burgess N., Donnett J.G., Frackowiak R.S., Frith C.D., O'Keefe J.
ISSN
0036-8075 (Print)
ISSN-L
0036-8075
Statut éditorial
Publié
Date de publication
1998
Volume
280
Numéro
5365
Pages
921-924
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
The neural basis of navigation by humans was investigated with functional neuroimaging of brain activity during navigation in a familiar, yet complex virtual reality town. Activation of the right hippocampus was strongly associated with knowing accurately where places were located and navigating accurately between them. Getting to those places quickly was strongly associated with activation of the right caudate nucleus. These two right-side brain structures function in the context of associated activity in right inferior parietal and bilateral medial parietal regions that support egocentric movement through the virtual town, and activity in other left-side regions (hippocampus, frontal cortex) probably involved in nonspatial aspects of navigation. These findings outline a network of brain areas that support navigation in humans and link the functions of these regions to physiological observations in other mammals.
Mots-clé
Brain Mapping, Caudate Nucleus/blood supply, Caudate Nucleus/physiology, Cues, Frontal Lobe/blood supply, Frontal Lobe/physiology, Hippocampus/blood supply, Hippocampus/physiology, Humans, Male, Memory, Neural Pathways, Orientation, Parietal Lobe/blood supply, Parietal Lobe/physiology, Psychomotor Performance, Regional Blood Flow, Space Perception, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
16/09/2011 16:29
Dernière modification de la notice
20/08/2019 12:49
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