Perchance to dream: solving the mystery of sleep through genetic analysis.

Détails

ID Serval
serval:BIB_11110B656DE4
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Perchance to dream: solving the mystery of sleep through genetic analysis.
Périodique
Journal of Neurobiology
Auteur(s)
Shaw P.J., Franken P.
ISSN
0022-3034[print], 0022-3034[linking]
Statut éditorial
Publié
Date de publication
2003
Volume
54
Numéro
1
Pages
179-202
Langue
anglais
Résumé
Sleep has been identified in all mammals and nonmammalian vertebrates that have been critically evaluated. In addition, sleep-like states have also been identified and described in several invertebrates. Despite this prevalence throughout the animal kingdom, the function of sleep remains a mystery. The completion of several genome sequencing projects has led to the expectation that fundamental aspects of sleep can be elucidated through genetic dissection. Indeed, studies in both the mouse and fly have begun to reveal tantalizing suggestions about the underlying principles that regulate sleep homeostasis. In this article we will review recent studies that have used genetic techniques to evaluate sleep in the fruit fly and the mouse.
Mots-clé
Animals, Animals, Inbred Strains, Chromosome Mapping, Circadian Rhythm/genetics, Circadian Rhythm/physiology, Dreams/physiology, Drosophila melanogaster, Electroencephalography, Gene Expression Regulation, Genetic Techniques, Homeostasis/genetics, Homeostasis/physiology, Mice, Phenotype, Quantitative Trait Loci, Sleep/genetics, Sleep/physiology, Sleep Deprivation/genetics, Sleep Deprivation/physiopathology, Sleep, REM/genetics, Sleep, REM/physiology
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 16:31
Dernière modification de la notice
20/08/2019 13:38
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