Le traitement de l'échinococcose alvéolaire humaine: une approche multidisciplinaire [Treatment of alveolar echinococcosis: a multidisciplinary task]

Détails

ID Serval
serval:BIB_10C6A638A569
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Le traitement de l'échinococcose alvéolaire humaine: une approche multidisciplinaire [Treatment of alveolar echinococcosis: a multidisciplinary task]
Périodique
Bulletin de l'Académie Nationale de Médecine
Auteur(s)
Mantion G., Bresson-Hadni S., Vuitton D.A., Wen H., Chapuis Y., Gillet M.
ISSN
0001-4079
Statut éditorial
Publié
Date de publication
2008
Volume
192
Numéro
6
Pages
1151-1158
Langue
français
Notes
Publication types: English Abstract ; Journal Article Publication Status: ppublish
Résumé
Alveolar echinococcosis is characterized by a long asymptomatic period but, without treatment, up to 80% of patients may die within ten years of diagnosis. Owing to a lack of fast-acting and fully effective chemotherapy, partial radical hepatic resection is the only chance of cure. One-third of patients are now treated in this way, and complex vascular and biliary reconstruction procedures are sometimes necessary. Liver transplantation may also be indicated for highly selected patients (about 5%) with life-threatening complications after failure of other treatments. Interventional radiology and endoscopy can be used to drain liver abscesses and/or infected and obstructed bile ducts, either as palliative procedures or as a bridge to radical resection. Parasitostatic benzimidazole therapy, especially based on continuous albendazole administration, is mandatory for at least two years after radical resection, and for life in inoperable patients.
Mots-clé
Animals, Antiprotozoal Agents/therapeutic use, Echinococcosis, Hepatic/surgery, Echinococcosis, Pulmonary/therapy, Humans, Liver Transplantation, Patient Care Team
Pubmed
Web of science
Création de la notice
08/02/2010 16:26
Dernière modification de la notice
20/08/2019 12:38
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