Le traitement de l'échinococcose alvéolaire humaine: une approche multidisciplinaire [Treatment of alveolar echinococcosis: a multidisciplinary task]

Details

Serval ID
serval:BIB_10C6A638A569
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Le traitement de l'échinococcose alvéolaire humaine: une approche multidisciplinaire [Treatment of alveolar echinococcosis: a multidisciplinary task]
Journal
Bulletin de l'Académie Nationale de Médecine
Author(s)
Mantion G., Bresson-Hadni S., Vuitton D.A., Wen H., Chapuis Y., Gillet M.
ISSN
0001-4079
Publication state
Published
Issued date
2008
Volume
192
Number
6
Pages
1151-1158
Language
french
Notes
Publication types: English Abstract ; Journal Article Publication Status: ppublish
Abstract
Alveolar echinococcosis is characterized by a long asymptomatic period but, without treatment, up to 80% of patients may die within ten years of diagnosis. Owing to a lack of fast-acting and fully effective chemotherapy, partial radical hepatic resection is the only chance of cure. One-third of patients are now treated in this way, and complex vascular and biliary reconstruction procedures are sometimes necessary. Liver transplantation may also be indicated for highly selected patients (about 5%) with life-threatening complications after failure of other treatments. Interventional radiology and endoscopy can be used to drain liver abscesses and/or infected and obstructed bile ducts, either as palliative procedures or as a bridge to radical resection. Parasitostatic benzimidazole therapy, especially based on continuous albendazole administration, is mandatory for at least two years after radical resection, and for life in inoperable patients.
Keywords
Animals, Antiprotozoal Agents/therapeutic use, Echinococcosis, Hepatic/surgery, Echinococcosis, Pulmonary/therapy, Humans, Liver Transplantation, Patient Care Team
Pubmed
Web of science
Create date
08/02/2010 16:26
Last modification date
20/08/2019 12:38
Usage data