Aquaporins in neurological disorders

Détails

Ressource 1Télécharger: Hirt Aquaporins CTN.pdf (361.35 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY-NC 4.0
ID Serval
serval:BIB_0FF38E1931E3
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Aquaporins in neurological disorders
Périodique
Clinical and Translational Neuroscience
Auteur⸱e⸱s
Hirt Lorenz, Price Melanie, Benakis Corinne, Badaut Jérôme
ISSN
2514-183X
2514-183X
Statut éditorial
Publié
Date de publication
01/2018
Peer-reviewed
Oui
Volume
2
Numéro
1
Pages
2514183X1775290
Langue
anglais
Résumé
Aquaporins (AQPs) are water channel molecules that allow the passage of water through the lipid bilayers of cell membranes. AQP1, AQP4 and AQP9 are expressed in the central nervous system and AQP4 is well known as the target of auto-antibodies in Devic’s neuromyelitis optica. The role of AQPs in facilitating water movements suggests a link with
oedema formation and resolution in the brain. Furthermore, AQPs are also involved in process formation in glial cells with a close link to neuroinflammation. This mini-review gives an overview of what is currently known about the role of AQPs in different neurological disorders.
Open Access
Oui
Création de la notice
09/02/2018 12:19
Dernière modification de la notice
08/05/2020 7:08
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