Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery.
Détails
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Accès restreint UNIL
Etat: Public
Version: Final published version
Accès restreint UNIL
Etat: Public
Version: Final published version
ID Serval
serval:BIB_0E65A7CA68CA
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery.
Périodique
Journal of Surgical Oncology
ISSN
1096-9098 (Electronic)
ISSN-L
0022-4790
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
112
Numéro
5
Pages
544-554
Langue
anglais
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublishDocument Type: Review
Résumé
Lumbo-sacral chordoma is a rare, slow-growing tumor, arising from embryonic nothocordal remnants. Wide en bloc excision with clear margins remains mandatory to achieve satisfactory recurrence rates and disease-free survival. No chemotherapy has been demonstrated to be effective and radiotherapy is only marginally effective. Tyrosine kinase receptor inhibitors have showed encouraging results in locally advanced and metastatic chordoma. Reconstructive surgery may become very complex. Multidisciplinary approach in tertiary hospitals is always necessary. J. Surg. Oncol. 2015; 112:544-554. © 2015 Wiley Periodicals, Inc.
Pubmed
Web of science
Création de la notice
24/11/2015 18:15
Dernière modification de la notice
20/08/2019 13:35