Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_0E65A7CA68CA
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery.
Journal
Journal of Surgical Oncology
Author(s)
Garofalo F., di Summa P.G., Christoforidis D., Pracht M., Laudato P., Cherix S., Bouchaab H., Raffoul W., Demartines N., Matter M.
ISSN
1096-9098 (Electronic)
ISSN-L
0022-4790
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
112
Number
5
Pages
544-554
Language
english
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublishDocument Type: Review
Abstract
Lumbo-sacral chordoma is a rare, slow-growing tumor, arising from embryonic nothocordal remnants. Wide en bloc excision with clear margins remains mandatory to achieve satisfactory recurrence rates and disease-free survival. No chemotherapy has been demonstrated to be effective and radiotherapy is only marginally effective. Tyrosine kinase receptor inhibitors have showed encouraging results in locally advanced and metastatic chordoma. Reconstructive surgery may become very complex. Multidisciplinary approach in tertiary hospitals is always necessary. J. Surg. Oncol. 2015; 112:544-554. © 2015 Wiley Periodicals, Inc.
Pubmed
Web of science
Create date
24/11/2015 17:15
Last modification date
20/08/2019 12:35
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