Occupational asthma: new low-molecular-weight causal agents, 2000-2010

Détails

ID Serval
serval:BIB_0BE394E73434
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Occupational asthma: new low-molecular-weight causal agents, 2000-2010
Périodique
Journal of Allergy
Auteur⸱e⸱s
Pralong Jacques A., Cartier André, Vandenplas Olivier, Labrecque Manon
ISSN
1687-9791 (Electronic)
ISSN-L
1687-9783
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
2012
Pages
597306
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Background. More than 400 agents have been documented as causing occupational asthma (OA). The list of low-molecular-weight (LMW) agents that have been identified as potential causes of OA is constantly expanding, emphasizing the need to continually update our knowledge by reviewing the literature. Objective. The objective of this paper was to identify all new LMW agents causing occupational asthma reported during the period 2000-2010. Methods. A Medline search was performed using the keywords occupational asthma, new allergens, new causes, and low-molecular-weight agents. Results. We found 39 publications describing 41 new LMW causal agents, which belonged to the following categories: drugs (n = 12), wood dust (n = 11), chemicals (n = 8), metals (n = 4), biocides (n = 3), and miscellaneous (n = 3). The diagnosis of OA was confirmed through SIC for 35 of 41 agents, peak expiratory flow monitoring for three (3) agents, and the clinical history alone for three (3) agents. Immunological tests provided evidence supporting an IgE-mediated mechanism for eight (8) (20%) of the newly described agents. Conclusion. This paper highlights the importance of being alert to the occurrence of new LMW sensitizers, which can elicit OA. The immunological mechanism is explained by a type I hypersensitivity reaction in 20% of all newly described LMW agents.

Pubmed
Open Access
Oui
Création de la notice
11/09/2017 17:32
Dernière modification de la notice
20/08/2019 13:33
Données d'usage