Signaling via vascular endothelial growth factor receptors.

Détails

ID Serval
serval:BIB_0B6F82E2F61D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Signaling via vascular endothelial growth factor receptors.
Périodique
Experimental Cell Research
Auteur⸱e⸱s
Petrova T.V., Makinen T., Alitalo K.
ISSN
0014-4827 (Print)
ISSN-L
0014-4827
Statut éditorial
Publié
Date de publication
1999
Volume
253
Numéro
1
Pages
117-130
Langue
anglais
Résumé
Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses. The review focuses on the signaling pathways that are initiated from these receptors and the recently identified VEGF coreceptor neuroplilin-1.
Mots-clé
Endothelium, Vascular/physiology, Gene Expression Regulation, Neovascularization, Pathologic, Neovascularization, Physiologic, Nerve Tissue Proteins/metabolism, Neuropilin-1, Receptor Protein-Tyrosine Kinases/metabolism, Receptors, Growth Factor/metabolism, Receptors, Vascular Endothelial Growth Factor, Signal Transduction
Pubmed
Web of science
Création de la notice
20/12/2012 15:52
Dernière modification de la notice
20/08/2019 12:33
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