Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes

Détails

ID Serval
serval:BIB_097F4F3C0326
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes
Périodique
FEBS Letters
Auteur(s)
Masson  D., Zamai  M., Tschopp  J.
ISSN
0014-5793 (Print)
Statut éditorial
Publié
Date de publication
11/1986
Volume
208
Numéro
1
Pages
84-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov 10
Résumé
A serine esterase called granzyme A, which is specifically expressed in cytolytic lymphocytes has been characterized. It is a disulfide-linked dimer and exhibits a trypsin-like specificity cleaving best after Arg. N-terminal sequence analysis revealed that granzyme A is identical to a protease recently predicted from a cloned CTL-specific gene.
Mots-clé
Amino Acid Sequence Electrophoresis, Polyacrylamide Gel Endopeptidases/*blood/genetics *Genes Granzymes *Serine Endopeptidases T-Lymphocytes, Cytotoxic/*enzymology
Pubmed
Web of science
Création de la notice
24/01/2008 15:19
Dernière modification de la notice
20/08/2019 12:31
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