Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes
Details
Serval ID
serval:BIB_097F4F3C0326
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes
Journal
FEBS Letters
ISSN
0014-5793 (Print)
Publication state
Published
Issued date
11/1986
Volume
208
Number
1
Pages
84-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Nov 10
Research Support, Non-U.S. Gov't --- Old month value: Nov 10
Abstract
A serine esterase called granzyme A, which is specifically expressed in cytolytic lymphocytes has been characterized. It is a disulfide-linked dimer and exhibits a trypsin-like specificity cleaving best after Arg. N-terminal sequence analysis revealed that granzyme A is identical to a protease recently predicted from a cloned CTL-specific gene.
Keywords
Amino Acid Sequence
Electrophoresis, Polyacrylamide Gel
Endopeptidases/*blood/genetics
*Genes
Granzymes
*Serine Endopeptidases
T-Lymphocytes, Cytotoxic/*enzymology
Pubmed
Web of science
Create date
24/01/2008 16:19
Last modification date
20/08/2019 13:31
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