Apport des techniques d'immunohistochimie et d'hybridation in situ dans les affections dues ou associées au virus d'Epstein-Barr [Contribution of immunohistochemistry and in situ hybridization techniques in diseases caused by or associated with Epstein-Barr virus].
Détails
ID Serval
serval:BIB_0921372D64B7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Apport des techniques d'immunohistochimie et d'hybridation in situ dans les affections dues ou associées au virus d'Epstein-Barr [Contribution of immunohistochemistry and in situ hybridization techniques in diseases caused by or associated with Epstein-Barr virus].
Périodique
Archives D'anatomie et De Cytologie Pathologiques
ISSN
0242-6498; 0395-501X (Print)
ISSN-L
0395-501X
Statut éditorial
Publié
Date de publication
1992
Peer-reviewed
Oui
Volume
40
Numéro
2-3
Pages
95-104
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Résumé
Epstein-Barr virus is associated with many diseases. Today, the pathologist may study either by immunohistochemistry or in situ hybridization on tissue sections: EBV genome, EBV messenger RNA, EBV latent and replicative proteins. Several technics can be performed on fixed paraffin-embedded tissue to demonstrate the presence of EBV DNA, EBER-1 RNA, LMP-1 protein. Frozen tissues are required for the study of EBNA-2, ZEBRA and replicating proteins expression. The results, obtained during the study of benign and malignant proliferations always or often associated with EBV, such as infectious mononucleosis, Burkitt's lymphomas, AIDS associated lymphomas, lymphoproliferations in immunocompromised patients, Hodgkin's disease, and some epithelial proliferations, are summarized.
Mots-clé
Acquired Immunodeficiency Syndrome/complications, Burkitt Lymphoma/complications, Burkitt Lymphoma/diagnosis, DNA, Viral/genetics, Herpesvirus 4, Human/isolation & purification, Hodgkin Disease/diagnosis, Humans, Immunohistochemistry/methods, In Situ Hybridization, Infectious Mononucleosis/diagnosis, Lymphoma/complications, Lymphoma, Non-Hodgkin/diagnosis, Lymphoproliferative Disorders/diagnosis, Nucleic Acid Hybridization/physiology, RNA, Viral/genetics
Pubmed
Création de la notice
13/10/2015 9:56
Dernière modification de la notice
20/08/2019 13:31