Secondary amyloidosis: a severe complication of ankylosing spondylitis. Two case-reports.

Détails

ID Serval
serval:BIB_07EDB0EE5D7B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Secondary amyloidosis: a severe complication of ankylosing spondylitis. Two case-reports.
Périodique
Joint, bone, spine : revue du rhumatisme
Auteur⸱e⸱s
Kovacsovics-Bankowski M., Zufferey P., So A.K., Gerster J.C.
ISSN
1297-319X
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
67
Numéro
2
Pages
129-33
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Résumé
STUDY OBJECTIVE: To report two cases of amyloidosis secondary to ankylosing spondylitis. PATIENTS AND RESULTS: Of the 47 ankylosing spondylitis patients who have received follow-up at our department over the last few years, two have developed AA amyloidosis. Both have extremely severe, long-standing joint disease, with virtually complete spinal ankylosis and destructive peripheral arthritis of the hips and wrists; one also has tarsal joint destruction. Renal dysfunction was the first manifestation of amyloidosis in both cases. One patient required chronic hemodialysis and developed peritonitis due to colonic perforation, probably at a site of amyloid deposition. CONCLUSIONS: Secondary amyloidosis is a rare complication of ankylosing spondylitis that can cause severe renal and gastrointestinal complications. No treatment capable of clearing established amyloid deposits is available to date.
Mots-clé
Adult, Amyloidosis, Humans, Male, Middle Aged, Spondylitis, Ankylosing
Pubmed
Web of science
Création de la notice
25/01/2008 8:39
Dernière modification de la notice
20/08/2019 12:30
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