FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded

Détails

Ressource 1Télécharger: REF.pdf (193.36 [Ko])
Etat: Public
Version: Final published version
Licence: Non spécifiée
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
ID Serval
serval:BIB_072223A553B5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded
Périodique
Bioinformatics
Auteur⸱e⸱s
Prilusky  J., Felder  C. E., Zeev-Ben-Mordehai  T., Rydberg  E. H., Man  O., Beckmann  J. S., Silman  I., Sussman  J. L.
ISSN
1367-4803 (Print)
Statut éditorial
Publié
Date de publication
08/2005
Volume
21
Numéro
16
Pages
3435-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Aug 15
Résumé
An easy-to-use, versatile and freely available graphic web server, FoldIndex is described: it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of Uversky and co-workers, which is based on the average residue hydrophobicity and net charge of the sequence. FoldIndex has an error rate comparable to that of more sophisticated fold prediction methods. Sliding windows permit identification of large regions within a protein that possess folding propensities different from those of the whole protein.
Mots-clé
*Algorithms Computer Graphics Computer Simulation Energy Transfer Internet *Models, Chemical *Models, Molecular Protein Conformation Protein Folding Proteins/analysis/*chemistry Sequence Alignment/*methods Sequence Analysis, Protein/*methods *Software Structure-Activity Relationship *User-Computer Interface
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 16:17
Dernière modification de la notice
14/02/2022 7:53
Données d'usage