Vascular Abnormalities Detected with Chest CT in COVID-19: Spectrum, Association with Parenchymal Lesions, Cardiac Changes, and Correlation with Clinical Severity (COVID-CAVA Study).

Détails

Ressource 1Télécharger: diagnostics-11-00606.pdf (1229.64 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_066B4C4BB1E0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Vascular Abnormalities Detected with Chest CT in COVID-19: Spectrum, Association with Parenchymal Lesions, Cardiac Changes, and Correlation with Clinical Severity (COVID-CAVA Study).
Périodique
Diagnostics
Auteur⸱e⸱s
Qanadli S.D., Sauter A.W., Alkadhi H., Christe A., Poletti P.A., Ebner L., Rotzinger D.C.
ISSN
2075-4418 (Print)
ISSN-L
2075-4418
Statut éditorial
Publié
Date de publication
29/03/2021
Peer-reviewed
Oui
Volume
11
Numéro
4
Pages
606
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
Although vascular abnormalities are thought to affect coronavirus disease 2019 (COVID-19) patients' outcomes, they have not been thoroughly characterized in large series of unselected patients. The Swiss national registry coronavirus-associated vascular abnormalities (CAVA) is a multicentric cohort of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who underwent a clinically indicated chest computed tomography (CT) aiming to assess the prevalence, severity, distribution, and prognostic value of vascular and non-vascular-related CT findings. Clinical outcomes, stratified as outpatient treatment, inpatient without mechanical ventilation, inpatient with mechanical ventilation, or death, will be correlated with CT and biological markers. The main objective is to assess the prevalence of cardiovascular abnormalities-including pulmonary embolism (PE), cardiac morphology, and vascular congestion. Secondary objectives include the predictive value of cardiovascular abnormalities in terms of disease severity and fatal outcome and the association of lung inflammation with vascular abnormalities at the segmental level. New quantitative approaches derived from CT imaging are developed and evaluated in this study. Patients with and without vascular abnormalities will be compared, which is supposed to provide insights into the prognostic role and potential impact of such signs on treatment strategy. Results are expected to enable the development of an integrative score combining both clinical data and imaging findings to predict outcomes.
Mots-clé
COVID-19, computed tomography, perfusion, pulmonary embolism, respiratory failure, vascular congestion
Pubmed
Web of science
Open Access
Oui
Création de la notice
04/04/2021 9:29
Dernière modification de la notice
21/11/2022 9:20
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