Patient respiratory-triggered quantitative T2 mapping in the pancreas.
Détails
Etat: Public
Version: de l'auteur⸱e
Licence: Non spécifiée
ID Serval
serval:BIB_062BCBEF74AC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Patient respiratory-triggered quantitative T2 mapping in the pancreas.
Périodique
Journal of magnetic resonance imaging
ISSN
1522-2586 (Electronic)
ISSN-L
1053-1807
Statut éditorial
Publié
Date de publication
08/2019
Peer-reviewed
Oui
Volume
50
Numéro
2
Pages
410-416
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Long acquisition times and motion sensitivity limit T <sub>2</sub> mapping in the abdomen. Accelerated mapping at 3 T may allow for quantitative assessment of diffuse pancreatic disease in patients during free-breathing.
To test the feasibility of respiratory-triggered quantitative T <sub>2</sub> analysis in the pancreas and correlate T <sub>2</sub> -values with age, body mass index, pancreatic location, main pancreatic duct dilatation, and underlying pathology.
Retrospective single-center pilot study.
Eighty-eight adults.
Ten-fold accelerated multiecho-spin-echo 3 T MRI sequence to quantify T <sub>2</sub> at 3 T.
Two radiologists independently delineated three regions of interest inside the pancreatic head, body, and tail for each acquisition. Means and standard deviations for T <sub>2</sub> values in these regions were determined. T <sub>2</sub> -value variation with demographic data, intraparenchymal location, pancreatic duct dilation, and underlying pancreatic disease was assessed.
Interreader reliability was determined by calculating the interclass coefficient (ICCs). T <sub>2</sub> values were compared for different pancreatic locations by analysis of variance (ANOVA). Interpatient associations between T <sub>2</sub> values and demographical, clinical, and radiological data were calculated (ANOVA).
The accelerated T <sub>2</sub> mapping sequence was successfully performed in all participants (mean acquisition time, 2:48 ± 0:43 min). Low T <sub>2</sub> value variability was observed across all patients (intersubject) (head: 60.2 ± 8.3 msec, body: 63.9 ± 11.5 msec, tail: 66.8 ± 16.4 msec). Interreader agreement was good (ICC, 0.82, 95% confidence interval: 0.77-0.86). T <sub>2</sub> -values differed significantly depending on age (P < 0.001), location (P < 0.001), main pancreatic duct dilatation (P < 0.001), and diffuse pancreatic disease (P < 0.03).
The feasibility of accelerated T <sub>2</sub> mapping at 3 T in moving abdominal organs was demonstrated in the pancreas, since T <sub>2</sub> values were stable and reproducible. In the pancreatic parenchyma, T <sub>2</sub> -values were significantly dependent on demographic and clinical parameters.
4 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;50:410-416.
To test the feasibility of respiratory-triggered quantitative T <sub>2</sub> analysis in the pancreas and correlate T <sub>2</sub> -values with age, body mass index, pancreatic location, main pancreatic duct dilatation, and underlying pathology.
Retrospective single-center pilot study.
Eighty-eight adults.
Ten-fold accelerated multiecho-spin-echo 3 T MRI sequence to quantify T <sub>2</sub> at 3 T.
Two radiologists independently delineated three regions of interest inside the pancreatic head, body, and tail for each acquisition. Means and standard deviations for T <sub>2</sub> values in these regions were determined. T <sub>2</sub> -value variation with demographic data, intraparenchymal location, pancreatic duct dilation, and underlying pancreatic disease was assessed.
Interreader reliability was determined by calculating the interclass coefficient (ICCs). T <sub>2</sub> values were compared for different pancreatic locations by analysis of variance (ANOVA). Interpatient associations between T <sub>2</sub> values and demographical, clinical, and radiological data were calculated (ANOVA).
The accelerated T <sub>2</sub> mapping sequence was successfully performed in all participants (mean acquisition time, 2:48 ± 0:43 min). Low T <sub>2</sub> value variability was observed across all patients (intersubject) (head: 60.2 ± 8.3 msec, body: 63.9 ± 11.5 msec, tail: 66.8 ± 16.4 msec). Interreader agreement was good (ICC, 0.82, 95% confidence interval: 0.77-0.86). T <sub>2</sub> -values differed significantly depending on age (P < 0.001), location (P < 0.001), main pancreatic duct dilatation (P < 0.001), and diffuse pancreatic disease (P < 0.03).
The feasibility of accelerated T <sub>2</sub> mapping at 3 T in moving abdominal organs was demonstrated in the pancreas, since T <sub>2</sub> values were stable and reproducible. In the pancreatic parenchyma, T <sub>2</sub> -values were significantly dependent on demographic and clinical parameters.
4 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;50:410-416.
Pubmed
Web of science
Open Access
Oui
Création de la notice
16/01/2019 8:14
Dernière modification de la notice
12/04/2023 5:54
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