Patient respiratory-triggered quantitative T<sub>2</sub> mapping in the pancreas.

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Serval ID
serval:BIB_062BCBEF74AC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Patient respiratory-triggered quantitative T<sub>2</sub> mapping in the pancreas.
Journal
Journal of magnetic resonance imaging
Author(s)
Vietti Violi N., Hilbert T., Bastiaansen JAM, Knebel J.F., Ledoux J.B., Stemmer A., Meuli R., Kober T., Schmidt S.
ISSN
1522-2586 (Electronic)
ISSN-L
1053-1807
Publication state
Published
Issued date
08/2019
Peer-reviewed
Oui
Volume
50
Number
2
Pages
410-416
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Long acquisition times and motion sensitivity limit T <sub>2</sub> mapping in the abdomen. Accelerated mapping at 3 T may allow for quantitative assessment of diffuse pancreatic disease in patients during free-breathing.
To test the feasibility of respiratory-triggered quantitative T <sub>2</sub> analysis in the pancreas and correlate T <sub>2</sub> -values with age, body mass index, pancreatic location, main pancreatic duct dilatation, and underlying pathology.
Retrospective single-center pilot study.
Eighty-eight adults.
Ten-fold accelerated multiecho-spin-echo 3 T MRI sequence to quantify T <sub>2</sub> at 3 T.
Two radiologists independently delineated three regions of interest inside the pancreatic head, body, and tail for each acquisition. Means and standard deviations for T <sub>2</sub> values in these regions were determined. T <sub>2</sub> -value variation with demographic data, intraparenchymal location, pancreatic duct dilation, and underlying pancreatic disease was assessed.
Interreader reliability was determined by calculating the interclass coefficient (ICCs). T <sub>2</sub> values were compared for different pancreatic locations by analysis of variance (ANOVA). Interpatient associations between T <sub>2</sub> values and demographical, clinical, and radiological data were calculated (ANOVA).
The accelerated T <sub>2</sub> mapping sequence was successfully performed in all participants (mean acquisition time, 2:48 ± 0:43 min). Low T <sub>2</sub> value variability was observed across all patients (intersubject) (head: 60.2 ± 8.3 msec, body: 63.9 ± 11.5 msec, tail: 66.8 ± 16.4 msec). Interreader agreement was good (ICC, 0.82, 95% confidence interval: 0.77-0.86). T <sub>2</sub> -values differed significantly depending on age (P < 0.001), location (P < 0.001), main pancreatic duct dilatation (P < 0.001), and diffuse pancreatic disease (P < 0.03).
The feasibility of accelerated T <sub>2</sub> mapping at 3 T in moving abdominal organs was demonstrated in the pancreas, since T <sub>2</sub> values were stable and reproducible. In the pancreatic parenchyma, T <sub>2</sub> -values were significantly dependent on demographic and clinical parameters.
4 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;50:410-416.
Pubmed
Web of science
Open Access
Yes
Create date
16/01/2019 9:14
Last modification date
06/05/2020 17:00
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