A proven case of materno-foetal transfusion determined by cytogenetic and DNA analysis

Détails

ID Serval
serval:BIB_05CD8EC3983A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
A proven case of materno-foetal transfusion determined by cytogenetic and DNA analysis
Périodique
Clinical Genetics
Auteur(s)
Paoloni-Giacobino  A., Dutoit  M. H., Morris  M. A., Dahoun  S. P.
ISSN
0009-9163 (Print)
Statut éditorial
Publié
Date de publication
04/1999
Volume
55
Numéro
4
Pages
256-8
Notes
Case Reports
Journal Article --- Old month value: Apr
Résumé
We report a case of materno-foetal transfusion in a phenotypically normal male foetus after death in utero at the 35th week of gestation. We have used cytogenetic and polymerase chain reaction (PCR) microsatellite analysis to determine the presence of maternal cells in foetal blood collected by intracardiac puncture. In the intracardiac blood sample, maternal cells were estimated to comprise between 5 and 10% of nucleated foetal blood cells. When there is a suspicion of foetal genetic pathology, it is necessary to be aware that the foetal blood karyotype may be misrepresentative, as the analysed blood cells can indeed be of maternal origin.
Mots-clé
Adult Female *Fetal Death Fetomaternal Transfusion/*diagnosis/mortality Humans Karyotyping Male Microsatellite Repeats Polymerase Chain Reaction Polymorphism, Genetic Pregnancy
Pubmed
Web of science
Création de la notice
28/01/2008 12:14
Dernière modification de la notice
20/08/2019 12:27
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