Toward an understanding of the correlates of protective immunity to HIV infection

Détails

ID Serval
serval:BIB_0273EF843115
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Toward an understanding of the correlates of protective immunity to HIV infection
Périodique
Science
Auteur(s)
Haynes  B. F., Pantaleo  G., Fauci  A. S.
ISSN
0036-8075 (Print)
Statut éditorial
Publié
Date de publication
01/1996
Volume
271
Numéro
5247
Pages
324-8
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review --- Old month value: Jan 19
Résumé
Considerable progress has been made recently in understanding the genetic, immunologic and virologic factors in human immunodeficiency virus (HIV)-infected individuals who either rapidly progress or do not progress to acquired immunodeficiency syndrome (AIDS). In addition, detection of HIV-specific immune responses in HIV-negative individuals who have been exposed to the virus multiple times suggests that natural immune responses to HIV may be protective in rare individuals. Understanding the correlates of protective immunity to HIV infection is critical to efforts to develop preventive HIV vaccines as well as to determine the feasibility of treating HIV infection by boosting immunity to HIV.
Mots-clé
AIDS Vaccines Acquired Immunodeficiency Syndrome/*immunology/virology Animals CD4-Positive T-Lymphocytes/immunology CD8-Positive T-Lymphocytes/immunology Cytokines/immunology Disease Progression HIV/immunology/physiology HIV Antibodies/*immunology HIV Infections/*immunology/virology HIV Seronegativity/immunology Humans Major Histocompatibility Complex T-Lymphocytes/*immunology Virus Replication
Pubmed
Web of science
Création de la notice
25/01/2008 16:14
Dernière modification de la notice
20/08/2019 13:24
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