Primary focal prostate radiotherapy: Do all patients really need whole-prostate irradiation?
Détails
ID Serval
serval:BIB_00F99FD62C6A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Primary focal prostate radiotherapy: Do all patients really need whole-prostate irradiation?
Périodique
Critical reviews in oncology/hematology
ISSN
1879-0461 (Electronic)
ISSN-L
1040-8428
Statut éditorial
Publié
Date de publication
09/2016
Peer-reviewed
Oui
Volume
105
Pages
100-111
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
To review the available data about focal primary partial prostate irradiation (focal radiotherapy, FRT) for early prostate cancer.
Medline search for English language full paper on primary FRT for early prostate cancer including review articles, planning studies or patient series (clinical outcome available) published before May 31, 2015.
22 papers have been found: 11 review articles, 4 planning studies and 7 patient series. Eleven review articles were dedicated to all types of focal therapy including FRT and 2 to FRT only. All planning studies included brachytherapy and showed excellent organ-at-risk sparing. Patient series included together 715 patients (99% treated with brachytherapy) and showed promising tumour control in low-risk cancer. In intermediate-risk tumours, FRT might be suboptimal.
Primary FRT is feasible in early prostate cancer. As any other focal therapy, FRT remains investigational until numerous questions are answered.
Medline search for English language full paper on primary FRT for early prostate cancer including review articles, planning studies or patient series (clinical outcome available) published before May 31, 2015.
22 papers have been found: 11 review articles, 4 planning studies and 7 patient series. Eleven review articles were dedicated to all types of focal therapy including FRT and 2 to FRT only. All planning studies included brachytherapy and showed excellent organ-at-risk sparing. Patient series included together 715 patients (99% treated with brachytherapy) and showed promising tumour control in low-risk cancer. In intermediate-risk tumours, FRT might be suboptimal.
Primary FRT is feasible in early prostate cancer. As any other focal therapy, FRT remains investigational until numerous questions are answered.
Mots-clé
Brachytherapy, Clinical Trials as Topic, Humans, Male, Prostatic Neoplasms/diagnosis, Prostatic Neoplasms/radiotherapy
Pubmed
Création de la notice
19/07/2016 18:41
Dernière modification de la notice
20/08/2019 13:23
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