When orthologs diverge between human and mouse.

Détails

Ressource 1Télécharger: BIB_006579177FCC.P001.pdf (90.56 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_006579177FCC
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
When orthologs diverge between human and mouse.
Périodique
Briefings in Bioinformatics
Auteur(s)
Gharib W.H., Robinson-Rechavi M.
ISSN
1477-4054 (Electronic)
ISSN-L
1467-5463
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
12
Numéro
5
Pages
436-441
Langue
anglais
Résumé
Despite the common assumption that orthologs usually share the same function, there have been various reports of divergence between orthologs, even among species as close as mammals. The comparison of mouse and human is of special interest, because mouse is often used as a model organism to understand human biology. We review the literature on evidence for divergence between human and mouse orthologous genes, and discuss it in the context of biomedical research.
Pubmed
Web of science
Open Access
Oui
Création de la notice
11/05/2011 9:17
Dernière modification de la notice
20/08/2019 13:22
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