Ionotropic receptors (IRs): chemosensory ionotropic glutamate receptors in Drosophila and beyond.

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State: Public
Version: Final published version
Serval ID
serval:BIB_FE442C4FF36A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Ionotropic receptors (IRs): chemosensory ionotropic glutamate receptors in Drosophila and beyond.
Journal
Insect Biochemistry and Molecular Biology
Author(s)
Rytz R., Croset V., Benton R.
ISSN
1879-0240 (Electronic)
ISSN-L
0965-1748
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
43
Number
9
Pages
888-897
Language
english
Abstract
Ionotropic Receptors (IRs) are a recently characterized family of olfactory receptors in the fruit fly, Drosophila melanogaster. IRs are not related to insect Odorant Receptors (ORs), but rather have evolved from ionotropic glutamate receptors (iGluRs), a conserved family of synaptic ligand-gated ion channels. Here, we review the expression and function of IRs in Drosophila, highlighting similarities and differences with iGluRs. We also briefly describe the organization of the neuronal circuits in which IRs function, comparing and contrasting them with the sensory pathways expressing ORs. Finally, we summarize the bioinformatic identification and initial characterization of IRs in other species, which imply an evolutionarily conserved role for these receptors in chemosensation in insects and other protostomes.
Pubmed
Web of science
Open Access
Yes
Create date
17/04/2013 16:56
Last modification date
20/08/2019 16:28
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