Prédire la survenue d'un diabète: la place de scores cliniques et/ou génétiques [Genetic and/or clinical scores to anticipate the onset of diabetes]

Details

Serval ID
serval:BIB_F9D3FEF47C1A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Prédire la survenue d'un diabète: la place de scores cliniques et/ou génétiques [Genetic and/or clinical scores to anticipate the onset of diabetes]
Journal
Revue Médicale Suisse
Author(s)
Waeber Gérard, Mooser V., Vollenweider Peter
ISSN
1660-9379
Publication state
Published
Issued date
2009
Volume
5
Number
223
Pages
2136-2138, 2140-2141
Language
french
Notes
Publication types: English Abstract ; Journal Article Publication Status: ppublish
Abstract
Diabetes represents an important health burden on our society: for example in Lausanne (Switzerland) 16% of the adult population have abnormal glucose homeostasis and 6% have diabetes, of which about a third is not aware. Some guidelines identify the "at risk" population for which screening seems indicated. Simple clinical scores have been developed at allow to better estimate the risk of diabetes and hence to potentially better target screening of the disease. The recent discovery of more that 18 genetic variants associated with an increased risk to develop the diseased has allowed to include individual genotype into genetic risk scores. We will discuss in this article the usefulness of these genetic score, how they compare to clinical score, their implication for clinical practice as well as their potential ethical or economical consequences.
Pubmed
Create date
24/01/2010 12:54
Last modification date
20/08/2019 16:25
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