Prédire la survenue d'un diabète: la place de scores cliniques et/ou génétiques [Genetic and/or clinical scores to anticipate the onset of diabetes]

Détails

ID Serval
serval:BIB_F9D3FEF47C1A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Prédire la survenue d'un diabète: la place de scores cliniques et/ou génétiques [Genetic and/or clinical scores to anticipate the onset of diabetes]
Périodique
Revue Médicale Suisse
Auteur(s)
Waeber Gérard, Mooser V., Vollenweider Peter
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
2009
Volume
5
Numéro
223
Pages
2136-2138, 2140-2141
Langue
français
Notes
Publication types: English Abstract ; Journal Article Publication Status: ppublish
Résumé
Diabetes represents an important health burden on our society: for example in Lausanne (Switzerland) 16% of the adult population have abnormal glucose homeostasis and 6% have diabetes, of which about a third is not aware. Some guidelines identify the "at risk" population for which screening seems indicated. Simple clinical scores have been developed at allow to better estimate the risk of diabetes and hence to potentially better target screening of the disease. The recent discovery of more that 18 genetic variants associated with an increased risk to develop the diseased has allowed to include individual genotype into genetic risk scores. We will discuss in this article the usefulness of these genetic score, how they compare to clinical score, their implication for clinical practice as well as their potential ethical or economical consequences.
Pubmed
Création de la notice
24/01/2010 13:54
Dernière modification de la notice
03/03/2018 22:54
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