High-field dissolution dynamic nuclear polarization of [1-(13)C]pyruvic acid.

Details

Serval ID
serval:BIB_F70A128649AC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
High-field dissolution dynamic nuclear polarization of [1-(13)C]pyruvic acid.
Journal
Physical Chemistry Chemical Physics : Pccp
Author(s)
Yoshihara H.A., Can E., Karlsson M., Lerche M.H., Schwitter J., Comment A.
ISSN
1463-9084 (Electronic)
ISSN-L
1463-9076
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
18
Number
18
Pages
12409-12413
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
[1-(13)C]pyruvate is the most widely used hyperpolarized metabolic magnetic resonance imaging agent. Using a custom-built 7.0 T polarizer operating at 1.0 K and trityl radical-doped [1-(13)C]pyruvic acid, unextrapolated solution-state (13)C polarization greater than 60% was measured after dissolution and rapid transfer to a spectrometer magnet, demonstrating the signal enhancement attainable using optimized hardware. Slower rates of polarization under these conditions can be largely overcome with higher radical concentrations.
Pubmed
Web of science
Create date
03/05/2016 16:31
Last modification date
20/08/2019 16:23
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